The substances were identified by comparing hazardous chemical inventories, the Replace Now! List. and the TEDX list of endocrine disruptors from publicly available databases of food contact substances. Databases of substances in contact with food including the list of authorized food additives in the USA published by the Pew Charitable Trusts in 2013, that of the European Food Safety Authority (EFSA), the list of substances in contact with non-plastic foods of the ESCO Working Group and Annex I of CE 10/2011 including plastic substances in contact with food authorized for use in Europe.
Many of the 175 substances identified have been classified as carcinogenic, mutagenic or toxic to reproduction. Others are considered to cause interference with the hormonal system, they are called endocrine disruptors. A third group of chemicals are considered persistent and bioaccumulative.